For a long time now, the Choline vs. Alpha-G PC debate has been well discussed within the natural supplement community. The simple truth, however, is that there is really no “official” norm that can be objectively proved right or wrong. Most people seem to prefer choline and inositol to be the best overall source of vital nutrients for their bodies. In addition, choline bitartrate supplements are also widely used as a dietary supplement for a broad variety of health conditions, including Alzheimer’s, cancer, Parkinson’s, Multiple Sclerosis, etc. There are many different choline sources available on the market today, including prescription (as well as over-the-counter) and non-prescription supplemental types of choline.

What is choline bitartrate?

Choline is a basic unit of the vitamin class considered to be necessary for the normal function of any cell in the human body, as well as for the production of new cells. Choline works by ensuring that neurotransmitters such as serotonin and dopamine are formed at high levels and in the right amounts in our bodies. In addition, choline allows our bodies to make a variety of essential hormones and enzymes.

When choline and inositol are combined, they function in combination to further improve brain neurotransmitter synthesis. Since choline bitartrate is also a strong antioxidant, it helps to rid the body of free radicals and other toxins that can contribute to specific diseases. Many people have experienced choline supplement benefits without suffering from side effects or negative health reactions.

Choline deficiency causes many diseases of the liver and brain. The most popular problem is lack of energy. This is sometimes referred to as “liver sluggishness.” While other complications can arise from choline deficiency, some of the most common problems include memory loss, failure to concentrate, and depression. However, choline supplementation can relieve these symptoms in most severe cases.


Both choline and inositol are carried in cell membranes. One of them, choline, is carried in the plasma membrane and is used by the liver and brain; the other, inositol, is carried in the cell membrane and serves as a neurotransmitter. Choline deficiency results in low energy levels and induces fatigue and memory loss. On the other hand, when combined, choline and inositol offer the advantages of increased energy and power as well as increased mental function.

After three weeks of choline bitartrate administration, researchers found a substantial increase in the amount of neurons that were triggered when participants conducted a visual-spatial work-memory test. During the week, the participants performed a five-minute machine task. Then, after obtaining both placebo and choline bitartrate, they were tested for visual memory output. In addition, researchers measured the blood flow through the cerebral cortex, which is situated in the middle part of the brain. Previous studies have shown that the presence of choline helps to increase the amount of oxygen and nutrients flowing through the brain cortex.

The study showed that choline and inositol increased the number of neurons that were stimulated when the participants performed visual memory tasks. The researchers have measured the flow of blood through the brain cortex. Previous studies have shown that the presence of choline helps to increase the amount of oxygen and nutrients flowing through the brain cortex. Increased blood flow and increased nourishment to brain cells were observed when participants performed a visual-spatial work-memory task after taking choline and inositol. These findings indicate that choline and inositol may help to increase the development of neurotransmitters and neurohormones that help maintain healthy brain function.


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